@article {pmid13111274,
year = {1953},
author = {ROSIN, A and DOLJANSKI, F},
title = {Effect of hydroquinone on mitosis.},
journal = {Nature},
volume = {172},
number = {4390},
pages = {1151},
doi = {10.1038/1721151a0},
pmid = {13111274},
issn = {0028-0836},
mesh = {Cell Division/*drug effects ; Humans ; *Hydroquinones ; *Mitosis ; Quinones/*pharmacology ; },
}

Cell Division/*drug effects
Humans
*Hydroquinones
*Mitosis
Quinones/*pharmacology

@article {pmid13134255,
year = {1953},
author = {CARLSON, AJ and BREWER, NR},
title = {Toxicity studies on hydroquinone.},
journal = {Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)},
volume = {84},
number = {3},
pages = {684-688},
doi = {10.3181/00379727-84-20751},
pmid = {13134255},
issn = {0037-9727},
mesh = {Humans ; *Hydroquinones ; Quinones/*pharmacology ; },
}

Humans
*Hydroquinones
Quinones/*pharmacology

@article {pmid13103828,
year = {1953},
author = {MORRIS, GE},
title = {Synthetic rubbers; their chemistry and dermatological aspects.},
journal = {A.M.A. archives of industrial hygiene and occupational medicine},
volume = {8},
number = {6},
pages = {540-546},
pmid = {13103828},
issn = {0096-6703},
mesh = {*Butadienes ; *Dermatitis ; Dermatitis, Contact/*etiology ; *Elastomers ; Humans ; *Rubber ; },
}

*Butadienes
*Dermatitis
Dermatitis, Contact/*etiology
*Elastomers
Humans
*Rubber

@article {pmid13133656,
year = {1953},
author = {MUHLEMANN, H},
title = {[Anthraquinone and anthraquinone glycosides; the synthesis of Chrysazinhydroquinone-1-glycoside and chrysazin-9-anthrone-1-glycoside].},
journal = {Pharmaceutica acta Helvetiae},
volume = {28},
number = {11},
pages = {313-319},
pmid = {13133656},
issn = {0031-6865},
mesh = {Anthracenes/analogs & derivatives ; Anthraquinones/analogs & derivatives ; *Glycosides ; },
}

Anthracenes/analogs & derivatives
Anthraquinones/analogs & derivatives
*Glycosides

@article {pmid13106208,
year = {1953},
author = {FORMAN, L},
title = {A note on the depigmentary properties of monobenzylether of hydroquinone.},
journal = {The British journal of dermatology},
volume = {65},
number = {11},
pages = {406-409},
pmid = {13106208},
issn = {0007-0963},
mesh = {*Hydroquinones ; Phenols/*pharmacology ; Pigmentation/*drug effects ; },
}

*Hydroquinones
Phenols/*pharmacology
Pigmentation/*drug effects

@article {pmid13119443,
year = {1953},
author = {GIUGIARO, A and CASTELLI, D},
title = {[Trimethyl (methylphenyldodecyl) ammonium methyl sulfate in preoperative antisepsis].},
journal = {Minerva chirurgica},
volume = {8},
number = {18},
pages = {716-722},
pmid = {13119443},
issn = {0026-4733},
mesh = {*Ammonium Compounds ; *Anti-Infective Agents, Local ; *Antisepsis ; *Asepsis ; *Quaternary Ammonium Compounds ; *Sulfuric Acid Esters ; },
}

*Ammonium Compounds
*Anti-Infective Agents, Local
*Antisepsis
*Asepsis
*Quaternary Ammonium Compounds
*Sulfuric Acid Esters

@article {pmid13092950,
year = {1953},
author = {DENTON, CA and KELLOGG, WL},
title = {The vitamin B12 activity of eggs and some materials as affected by extraction in the presence of sodium cyanide or sodium bisulfite.},
journal = {Archives of biochemistry and biophysics},
volume = {46},
number = {1},
pages = {105-109},
doi = {10.1016/0003-9861(53)90173-8},
pmid = {13092950},
issn = {0003-9861},
mesh = {Cyanides/*pharmacology ; *Eggs ; *Sodium Cyanide ; Sulfates/*pharmacology ; *Sulfites ; *Vitamin B 12 ; },
}

Cyanides/*pharmacology
*Eggs
*Sodium Cyanide
Sulfates/*pharmacology
*Sulfites
*Vitamin B 12

@article {pmid13111902,
year = {1953},
author = {DEUFEL, J and GANSHIRT, H},
title = {[Studies on the effect of aristolochic acid on bacteria and cell division of Vicia faba L].},
journal = {Die Pharmazie},
volume = {8},
number = {8},
pages = {679-682},
pmid = {13111902},
issn = {0031-7144},
mesh = {*Acids ; *Aristolochic Acids ; Bacteria/*drug effects ; Cell Division/*drug effects ; *Fabaceae ; *Vicia ; *Vicia faba ; },
}

*Acids
*Aristolochic Acids
Bacteria/*drug effects
Cell Division/*drug effects
*Fabaceae
*Vicia
*Vicia faba

@article {pmid13080239,
year = {1953},
author = {MARKS, MM},
title = {Clinical re-evaluation of dorbane in the treatment of functional constipation.},
journal = {The American journal of digestive diseases},
volume = {20},
number = {8},
pages = {240-242},
doi = {10.1007/BF02893220},
pmid = {13080239},
issn = {0002-9211},
mesh = {Anthraquinones/analogs & derivatives ; *Cathartics ; Constipation/*therapy ; Humans ; },
}

Anthraquinones/analogs & derivatives
*Cathartics
Constipation/*therapy
Humans

@article {pmid13140498,
year = {1953},
author = {PARMENTIER, R and ASTALDI, G},
title = {[First research on the effects of hydroquinone on proliferation of human bone marrow cells cultivated in vitro].},
journal = {Bollettino della Societa italiana di biologia sperimentale},
volume = {29},
number = {7},
pages = {1315-1317},
pmid = {13140498},
issn = {0037-8771},
mesh = {Bone Marrow/*drug effects ; *Bone Marrow Cells ; Humans ; *Hydroquinones ; In Vitro Techniques ; Phenols/*pharmacology ; },
}

Bone Marrow/*drug effects
*Bone Marrow Cells
Humans
*Hydroquinones
In Vitro Techniques
Phenols/*pharmacology

@article {pmid13121614,
year = {1953},
author = {PARMENTIER, R and DUSTIN, P},
title = {[On the mechanism of the mitotic abnormalities induced by hydroquinone in animal tissues].},
journal = {Revue belge de pathologie et de medecine experimentale},
volume = {23},
number = {1},
pages = {20-30},
pmid = {13121614},
issn = {0370-3770},
mesh = {Animals ; Cell Division/*drug effects ; Humans ; *Hydroquinones ; Quinones/*pharmacology ; },
}

Animals
Cell Division/*drug effects
Humans
*Hydroquinones
Quinones/*pharmacology

@article {pmid13121322,
year = {1953},
author = {GRIANTI, V and BARTALINI, E},
title = {[The use of lipotropic substances, complex B and liver extracts in some cases of industrial liver disease].},
journal = {Rassegna di medicina industriale e di igiene del lavoro},
volume = {22},
number = {4-5},
pages = {220-232},
pmid = {13121322},
issn = {0370-6249},
mesh = {*Folic Acid ; Humans ; *Hydroquinones ; *Lipotropic Agents ; Liver/*poisoning ; *Liver Diseases ; Liver Extracts/*therapeutic use ; Vitamin B Complex/*therapeutic use ; },
}

*Folic Acid
Humans
*Hydroquinones
*Lipotropic Agents
Liver/*poisoning
*Liver Diseases
Liver Extracts/*therapeutic use
Vitamin B Complex/*therapeutic use

@article {pmid13111881,
year = {1953},
author = {GANSHIRT, H},
title = {[Isolation of aristolochic acid from various Aristolochiaceae and its quantitative determination].},
journal = {Die Pharmazie},
volume = {8},
number = {7},
pages = {584-592},
pmid = {13111881},
issn = {0031-7144},
mesh = {*Acids ; *Aristolochiaceae ; *Aristolochic Acids ; *Plants ; },
}

*Acids
*Aristolochiaceae
*Aristolochic Acids
*Plants

@article {pmid13065676,
year = {1953},
author = {HOFFMANN, CR},
title = {Indications for the use of diphenmethanil methyl sulfate (prantal) in the treatment of peptic ulcer.},
journal = {American practitioner and digest of treatment},
volume = {4},
number = {7},
pages = {464-468},
pmid = {13065676},
mesh = {*Diet ; Parasympatholytics/*therapeutic use ; Peptic Ulcer/*therapy ; *Piperidines ; *Sulfuric Acid Esters ; },
}

*Diet
Parasympatholytics/*therapeutic use
Peptic Ulcer/*therapy
*Piperidines
*Sulfuric Acid Esters

@article {pmid13116540,
year = {1953},
author = {PARMENTIER, R},
title = {[Fusorial action of hydroquinone in the rabbit].},
journal = {Comptes rendus des seances de la Societe de biologie et de ses filiales},
volume = {147},
number = {9-10},
pages = {935-937},
pmid = {13116540},
issn = {0037-9026},
mesh = {Animals ; Cell Division/*drug effects ; Chromosomes/*drug effects ; *Hydroquinones ; Rabbits ; },
}

Animals
Cell Division/*drug effects
Chromosomes/*drug effects
*Hydroquinones
Rabbits

@article {pmid13054610,
year = {1953},
author = {VLITOS, AJ and KING, LF and AUDUS, LJ},
title = {Fate of sodium 2, 4-dichloro-phenoxy-ethyl-sulphate in the soil.},
journal = {Nature},
volume = {171},
number = {4351},
pages = {523-524},
doi = {10.1038/171523a0},
pmid = {13054610},
issn = {0028-0836},
mesh = {*Herbicides ; *Sodium ; *Soil ; *Sulfates ; *Sulfuric Acid Esters ; },
}

*Herbicides
*Sodium
*Soil
*Sulfates
*Sulfuric Acid Esters

@article {pmid13036380,
year = {1953},
author = {VIVINO, AE and RITTER, G},
title = {Treatment of dysmenorrhea with a dioxolane.},
journal = {The Medical annals of the District of Columbia},
volume = {22},
number = {3},
pages = {117-8; passim},
pmid = {13036380},
issn = {0025-6986},
mesh = {*Cardiovascular Agents ; *Dioxolanes ; Dysmenorrhea/*therapy ; Female ; Humans ; Muscle Relaxants, Central/*therapeutic use ; },
}

*Cardiovascular Agents
*Dioxolanes
Dysmenorrhea/*therapy
Female
Humans
Muscle Relaxants, Central/*therapeutic use

@article {pmid13031149,
year = {1953},
author = {KEATS, AS and BEECHER, HK},
title = {The analgesic effectiveness of morphine solutions containing sodium bisulfite.},
journal = {Anesthesiology},
volume = {14},
number = {2},
pages = {140-142},
doi = {10.1097/00000542-195303000-00004},
pmid = {13031149},
issn = {0003-3022},
mesh = {*Analgesics ; *Morphine ; *Solutions ; *Sulfites ; },
}

*Analgesics
*Morphine
*Solutions
*Sulfites

@article {pmid13027282,
year = {1953},
author = {BIRD, MJ and FAHMY, OG},
title = {Cytogenetic analysis of the action of carcinogens and tumour inhibitors in Drosophila melanogaster. I. 1:2, 3:4-diepoxybutane.},
journal = {Proceedings of the Royal Society of London. Series B, Biological sciences},
volume = {140},
number = {901},
pages = {556-578},
doi = {10.1098/rspb.1953.0008},
pmid = {13027282},
issn = {0950-1193},
mesh = {Animals ; *Carcinogens ; *Cytogenetic Analysis ; *Diptera ; *Drosophila melanogaster ; *Epoxy Compounds ; *Genetics ; *Neoplasms ; },
}

Animals
*Carcinogens
*Cytogenetic Analysis
*Diptera
*Drosophila melanogaster
*Epoxy Compounds
*Genetics
*Neoplasms

@article {pmid13123785,
year = {1953},
author = {MILOSEVIC, MP and TODOROVIC, DB},
title = {Influence of sodium bisulphite on the absorption rate of acetylcholine and of 1-noradrenaline.},
journal = {Acta medica Iugoslavica},
volume = {7},
number = {3},
pages = {197-203},
pmid = {13123785},
issn = {0375-8338},
mesh = {Acetylcholine/*metabolism ; Humans ; Norepinephrine/*metabolism ; Sulfites/*pharmacology ; *Synaptic Transmission ; },
}

Acetylcholine/*metabolism
Humans
Norepinephrine/*metabolism
Sulfites/*pharmacology
*Synaptic Transmission

@article {pmid13079914,
year = {1953},
author = {BOREUS, LO and SANDBERG, F},
title = {The analgesic action of n-acetyl p-aminophenol and its combination with some other substances.},
journal = {Acta physiologica Scandinavica},
volume = {28},
number = {2-3},
pages = {266-271},
doi = {10.1111/j.1748-1716.1953.tb00979.x},
pmid = {13079914},
issn = {0001-6772},
mesh = {*Acetaminophen ; Aminophenols ; *Analgesics ; Humans ; Phenols/*pharmacology ; },
}

*Acetaminophen
Aminophenols
*Analgesics
Humans
Phenols/*pharmacology

@article {pmid13079913,
year = {1953},
author = {BOREUS, LO and SANDBERG, F},
title = {A comparison of some pharmacological effects of acetophenetidin and N-acetyl p-aminophenol.},
journal = {Acta physiologica Scandinavica},
volume = {28},
number = {2-3},
pages = {261-265},
doi = {10.1111/j.1748-1716.1953.tb00978.x},
pmid = {13079913},
issn = {0001-6772},
mesh = {*Acetaminophen ; Aminophenols ; *Analgesics ; *Analgesics, Non-Narcotic ; *Antipyretics ; Phenacetin/*pharmacology ; Phenols/*pharmacology ; },
}

*Acetaminophen
Aminophenols
*Analgesics
*Analgesics, Non-Narcotic
*Antipyretics
Phenacetin/*pharmacology
Phenols/*pharmacology

@article {pmid13015103,
year = {1952},
author = {WASE, AW and ALLISON, JB and MIGLIARESE, JF},
title = {The effect of 2-aminofluorene on the utilization of S35 DL-methionine.},
journal = {Science (New York, N.Y.)},
volume = {116},
number = {3020},
pages = {536-537},
doi = {10.1126/science.116.3020.536},
pmid = {13015103},
issn = {0036-8075},
mesh = {*Biochemical Phenomena ; Fluorenes/pharmacology ; Humans ; Liver/*metabolism ; Methionine/*metabolism ; },
}

*Biochemical Phenomena
Fluorenes/pharmacology
Humans
Liver/*metabolism
Methionine/*metabolism

@article {pmid13010217,
year = {1952},
author = {WITKOP, B and GOODWIN, S},
title = {Significance and rearrangements of quinol models of tyrosine metabolites.},
journal = {Experientia},
volume = {8},
number = {10},
pages = {377-379},
pmid = {13010217},
issn = {0014-4754},
mesh = {*Biochemical Phenomena ; Humans ; *Hydroquinones ; Tyrosine/*pharmacology ; },
}

*Biochemical Phenomena
Humans
*Hydroquinones
Tyrosine/*pharmacology

@article {pmid13008527,
year = {1952},
author = {STONE, CA and KOMRAD, EL and LOEW, ER},
title = {Adrenergic blocking properties of N-ethyl-N-(2-chloroethyl)-9-fluorenamine hydrochloride.},
journal = {Archives internationales de pharmacodynamie et de therapie},
volume = {92},
number = {1},
pages = {7-12},
pmid = {13008527},
issn = {0003-9780},
mesh = {*Adrenergic Agents ; *Fluorenes ; *Salts ; },
}

*Adrenergic Agents
*Fluorenes
*Salts

@article {pmid12996815,
year = {1952},
author = {HUNTER, AR},
title = {Strychnine dimethyl sulphate.},
journal = {Anaesthesia},
volume = {7},
number = {4},
pages = {206-210},
doi = {10.1111/j.1365-2044.1952.tb01471.x},
pmid = {12996815},
issn = {0003-2409},
mesh = {*Cardiovascular Agents ; *Muscle Relaxants, Central ; *Strychnine ; *Sulfuric Acid Esters ; },
}

*Cardiovascular Agents
*Muscle Relaxants, Central
*Strychnine
*Sulfuric Acid Esters

@article {pmid12978993,
year = {1952},
author = {ALLISON, JB and WASE, AW},
title = {The effects of dietary riboflavin and pantothenic acid on the metabolism of 2-aminofluorene.},
journal = {Cancer research},
volume = {12},
number = {9},
pages = {647-650},
pmid = {12978993},
issn = {0008-5472},
mesh = {*Carcinogens ; *Diet ; *Fluorenes ; Pantothenic Acid/*pharmacology ; Riboflavin/*pharmacology ; },
}

*Carcinogens
*Diet
*Fluorenes
Pantothenic Acid/*pharmacology
Riboflavin/*pharmacology

@article {pmid14925942,
year = {1952},
author = {GUTMANN, HR and KIELY, GE and KLEIN, M},
title = {The metabolism of 2-aminofluorene in the rat.},
journal = {Cancer research},
volume = {12},
number = {5},
pages = {350-355},
pmid = {14925942},
issn = {0008-5472},
mesh = {Animals ; Fluorenes/*metabolism ; Rats ; },
}

Animals
Fluorenes/*metabolism
Rats

@article {pmid14920505,
year = {1952},
author = {KELLY, KH and BIERMAN, HR and SHIMKIN, MB},
title = {Negative effects of oral monobenzyl ether of hydroquinone in malignant melanoma in man.},
journal = {Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)},
volume = {79},
number = {4},
pages = {589-590},
doi = {10.3181/00379727-79-19456},
pmid = {14920505},
issn = {0037-9727},
mesh = {*Anesthetics, General ; *Ether ; *Ethers ; Humans ; *Hydroquinones ; Male ; Melanoma/*therapy ; *Phenols ; },
}

*Anesthetics, General
*Ether
*Ethers
Humans
*Hydroquinones
Male
Melanoma/*therapy
*Phenols

@article {pmid14925271,
year = {1952},
author = {BIELSCHOWSKY, F and BIELSCHOWSKY, M},
title = {The carcinogenic activity of N-mono-methyl- and N-dimethyl-2-aminofluorene.},
journal = {British journal of cancer},
volume = {6},
number = {1},
pages = {89-92},
doi = {10.1038/bjc.1952.9},
pmid = {14925271},
issn = {0007-0920},
mesh = {*Carcinogens ; Fluorenes/analogs & derivatives ; },
}

*Carcinogens
Fluorenes/analogs & derivatives

@article {pmid14907500,
year = {1952},
author = {SVEDRES, EV and JENKINS, GL},
title = {Aminoacyl derivatives of 2-aminofluorene and 2,2'-diamino-9,9'-spirobifluorene.},
journal = {Journal of the American Pharmaceutical Association. American Pharmaceutical Association},
volume = {41},
number = {2:1},
pages = {68-71},
doi = {10.1002/jps.3030410206},
pmid = {14907500},
mesh = {*Fluorenes ; },
}

*Fluorenes

@article {pmid14904398,
year = {1951},
author = {ROBINSON, D and SMITH, JN and WILLIAMS, RT},
title = {Studies in detoxication. 40. The metabolism of nitrobenzene in the rabbit; o-, m- and p-nitrophenols, o-, m- and p-aminophenols and 4-nitrocatechol as metabolites of nitrobenzene.},
journal = {The Biochemical journal},
volume = {50},
number = {2},
pages = {228-235},
pmid = {14904398},
issn = {0264-6021},
mesh = {*Aminophenols ; Animals ; *Catechols ; *Nitrobenzenes ; *Nitrophenols ; Rabbits ; },
}

*Aminophenols
Animals
*Catechols
*Nitrobenzenes
*Nitrophenols
Rabbits

@article {pmid14911957,
year = {1951},
author = {MARGOLIN, S and DOYLE, M and GIBLIN, J and MAKOVSKY, A and SPOERLEIN, MT and STEPHENS, I and BERCHTOLD, H and BELLOFF, G and TISLOW, R},
title = {Pharmacological properties of a new parasympathetic blocking agent, N,N dimethyl 4-piperidylidene 1,1 diphenylmethane methyl sulfate (Prantal).},
journal = {Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)},
volume = {78},
number = {2},
pages = {576-580},
doi = {10.3181/00379727-78-19145},
pmid = {14911957},
issn = {0037-9727},
mesh = {*Benzhydryl Compounds ; *Parasympatholytics ; *Piperidines ; *Sulfuric Acid Esters ; },
}

*Benzhydryl Compounds
*Parasympatholytics
*Piperidines
*Sulfuric Acid Esters

@article {pmid14867896,
year = {1951},
author = {FISHER, AA},
title = {Treatment of chloasma with monobenzyl ether of hydroquinone.},
journal = {A.M.A. archives of dermatology and syphilology},
volume = {64},
number = {5},
pages = {645-646},
pmid = {14867896},
issn = {0096-5979},
mesh = {*Ether ; *Ethers ; Humans ; *Hydroquinones ; *Melanosis ; *Pigmentation ; *Quinones ; },
}

*Ether
*Ethers
Humans
*Hydroquinones
*Melanosis
*Pigmentation
*Quinones

@article {pmid14878951,
year = {1951},
author = {RAY, FE and PETERS, JH},
title = {Secretion by the stomach of potential carcinogens derived from 2-aminofluorene.},
journal = {British journal of cancer},
volume = {5},
number = {3},
pages = {364-369},
pmid = {14878951},
issn = {0007-0920},
mesh = {*Carcinogens ; *Fluorenes ; Humans ; *Stomach Neoplasms ; },
}

*Carcinogens
*Fluorenes
Humans
*Stomach Neoplasms

@article {pmid14875481,
year = {1951},
author = {MUHLEMANN, H},
title = {[Anthraquinone and anthraquinonglycosides; nuclear synthesis of frangulaemodin and of a chrysophanic acid isomer, (1,6-dioxy-3-methylanthraquinone)].},
journal = {Pharmaceutica acta Helvetiae},
volume = {26},
number = {6},
pages = {195-203},
pmid = {14875481},
issn = {0031-6865},
mesh = {Anthraquinones/analogs & derivatives ; *Coloring Agents ; *Isomerism ; },
}

Anthraquinones/analogs & derivatives
*Coloring Agents
*Isomerism

@article {pmid14843106,
year = {1951},
author = {LEA, AJ},
title = {Effect of hydroquinone monobenzyl ether on melanin formation in vitro.},
journal = {Nature},
volume = {167},
number = {4257},
pages = {906},
doi = {10.1038/167906a0},
pmid = {14843106},
issn = {0028-0836},
mesh = {*Hydroquinones ; In Vitro Techniques ; *Melanins ; },
}

*Hydroquinones
In Vitro Techniques
*Melanins

@article {pmid14844430,
year = {1951},
author = {ROBERTSON, C and LASH, J and CORNBLEET, T and GROSSMAN, MI},
title = {Effect of sodium bisulfite and rutin on action of epinephrine; the "bisulfite phenomenon" in man.},
journal = {Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)},
volume = {77},
number = {1},
pages = {164-167},
doi = {10.3181/00379727-77-18713},
pmid = {14844430},
issn = {0037-9727},
mesh = {*Epinephrine ; Humans ; *Rutin ; *Sulfites ; },
}

*Epinephrine
Humans
*Rutin
*Sulfites

@article {pmid14821859,
year = {1951},
author = {ORR, RJ and WILLIAMS, HL},
title = {The compositional heterogeneity of butadiene-styrene copolymers synthesized at 18 degrees C. in emulsion.},
journal = {Canadian journal of chemistry},
volume = {29},
number = {3},
pages = {270-283},
doi = {10.1139/v51-032},
pmid = {14821859},
issn = {0008-4042},
mesh = {*Butadienes ; *Emulsions ; *Polystyrenes ; *Styrenes ; },
}

*Butadienes
*Emulsions
*Polystyrenes
*Styrenes

@article {pmid14821858,
year = {1951},
author = {EMBREE, WH and MITCHELL, JM and WILLIAMS, HL},
title = {Compositional heterogeneity of butadiene-acrylonitrile copolymers prepared in emulsion at 5 degrees C.},
journal = {Canadian journal of chemistry},
volume = {29},
number = {3},
pages = {253-269},
doi = {10.1139/v51-031},
pmid = {14821858},
issn = {0008-4042},
mesh = {*Acrylonitrile ; *Butadienes ; *Emulsions ; *Polymers ; *Vinyl Compounds ; },
}

*Acrylonitrile
*Butadienes
*Emulsions
*Polymers
*Vinyl Compounds

@article {pmid14802254,
year = {1951},
author = {ISAGULIANTS, VI and ESAIAN, GT},
title = {[Synthesis of arylbutadienes].},
journal = {Doklady Akademii nauk SSSR},
volume = {76},
number = {4},
pages = {531-534},
pmid = {14802254},
issn = {0002-3264},
mesh = {*Butadienes ; *Erythromelalgia ; },
}

*Butadienes
*Erythromelalgia

@article {pmid14851579,
year = {1951},
author = {BALO, J and VANDOR, F and REINMAN, P},
title = {[Effect of hydroquinone on the growth of transmissible mice cancer].},
journal = {Kiserletes orvostudomany},
volume = {3},
number = {3},
pages = {191-194},
pmid = {14851579},
issn = {0023-1878},
mesh = {Animals ; *Hydroquinones ; Mice ; *Neoplasms ; },
}

Animals
*Hydroquinones
Mice
*Neoplasms

@article {pmid14804299,
year = {1951},
author = {HOPPE, JO and GOBLE, FC},
title = {The intravenous toxicity of sodium bisulfite.},
journal = {The Journal of pharmacology and experimental therapeutics},
volume = {101},
number = {1},
pages = {101-106},
pmid = {14804299},
issn = {0022-3565},
mesh = {Humans ; *Sulfites ; },
}

Humans
*Sulfites

@article {pmid14799615,
year = {1951},
author = {HERBUT, PA and KRAEMER, WH and JACKSEN, J},
title = {The effect of hepbisul (heptyl aldehyde-sodium bisulfite addition compound) and thyroxin on Walker rat carcinoma 256.},
journal = {The American journal of pathology},
volume = {27},
number = {1},
pages = {59-83},
pmid = {14799615},
issn = {0002-9440},
mesh = {*Aldehydes ; Animals ; *Neoplasms ; Rats ; *Sulfites ; *Thyroxine ; },
}

*Aldehydes
Animals
*Neoplasms
Rats
*Sulfites
*Thyroxine

@article {pmid14796634,
year = {1950},
author = {CUNNINGHAM, KG and MANSON, W and SPRING, FS and HUTCHINSON, SA},
title = {Cordycepin, a metabolic product isolated from cultures of Cordyceps militaris (Linn.) Link.},
journal = {Nature},
volume = {166},
number = {4231},
pages = {949},
doi = {10.1038/166949a0},
pmid = {14796634},
issn = {0028-0836},
mesh = {*Anti-Bacterial Agents ; *Antibiotics, Antitubercular ; *Cordyceps ; *Deoxyadenosines ; *Fungi ; Humans ; },
}

*Anti-Bacterial Agents
*Antibiotics, Antitubercular
*Cordyceps
*Deoxyadenosines
*Fungi
Humans

@article {pmid15432397,
year = {1950},
author = {MICKLER, EE and DIGGS, LW},
title = {The detection of the sickle cell trait; a comparison of the sealed moist preparation using capillary blood collected during venous stasis and the sodium bisulfite method.},
journal = {American journal of clinical pathology},
volume = {20},
number = {9},
pages = {861-864},
pmid = {15432397},
issn = {0002-9173},
mesh = {*Capillaries ; *Erythrocytes ; Humans ; *Sickle Cell Trait ; *Sulfites ; },
}

*Capillaries
*Erythrocytes
Humans
*Sickle Cell Trait
*Sulfites

@article {pmid14809783,
year = {1950},
author = {BOLIS, L},
title = {[Blastomogenic function of 2-acetylaminofluorene and 2-amino-fluorene].},
journal = {Tumori},
volume = {24},
number = {5},
pages = {244-250},
pmid = {14809783},
issn = {0300-8916},
mesh = {*2-Acetylaminofluorene ; *Carcinogens ; *Fluorenes ; *Neoplasms ; },
}

*2-Acetylaminofluorene
*Carcinogens
*Fluorenes
*Neoplasms

@article {pmid15411240,
year = {1950},
author = {POLLOCK, JH},
title = {Hyperpigmentation improved by treatment with monobenzyl ether of hydroquinone.},
journal = {Archives of dermatology and syphilology},
volume = {61},
number = {5},
pages = {873-875},
pmid = {15411240},
issn = {0096-6029},
mesh = {*Ether ; *Ethers ; Humans ; *Hydroquinones ; *Hyperpigmentation ; *Pigmentation ; },
}

*Ether
*Ethers
Humans
*Hydroquinones
*Hyperpigmentation
*Pigmentation

@article {pmid15428987,
year = {1950},
author = {GRUBER, CM and DE BERADINIS, CT and SHIELDS, HL and COPELAND, JE},
title = {A pharmacologic and toxicologic study of heptyl aldehyde sodium bisulfite (hepbisul).},
journal = {The Journal of pharmacology and experimental therapeutics},
volume = {98},
number = {3},
pages = {274-285},
pmid = {15428987},
issn = {0022-3565},
mesh = {*Aldehydes ; Humans ; *Sulfites ; },
}

*Aldehydes
Humans
*Sulfites

@article {pmid15393974,
year = {1949},
author = {TREON, JF and SIGMON, H},
title = {The toxicity of methyl and ethyl acrylate.},
journal = {The Journal of industrial hygiene and toxicology},
volume = {31},
number = {6},
pages = {317-326},
pmid = {15393974},
issn = {0095-9030},
mesh = {*Acrylates ; Humans ; *Resins, Plant ; *Resins, Synthetic ; },
}

*Acrylates
Humans
*Resins, Plant
*Resins, Synthetic

@article {pmid15393973,
year = {1949},
author = {POZZANI, UC and WEIL, CS and CARPENTER, CP},
title = {Subacute vapor toxicity and range-finding data for ethyl acrylate.},
journal = {The Journal of industrial hygiene and toxicology},
volume = {31},
number = {6},
pages = {311-316},
pmid = {15393973},
issn = {0095-9030},
mesh = {*Acrylates ; *Gases ; *Resins, Plant ; *Resins, Synthetic ; },
}

*Acrylates
*Gases
*Resins, Plant
*Resins, Synthetic

@article {pmid15391927,
year = {1949},
author = {BROWN, BB and WERNER, HW},
title = {The parasympathetic depressant and antihistaminic action of substituted 1,3-dioxolanes.},
journal = {The Journal of pharmacology and experimental therapeutics},
volume = {97},
number = {2},
pages = {157-170},
pmid = {15391927},
issn = {0022-3565},
mesh = {*Central Nervous System Depressants ; *Dioxolanes ; *Histamine ; Humans ; *Nervous System ; },
}

*Central Nervous System Depressants
*Dioxolanes
*Histamine
Humans
*Nervous System

@article {pmid18133072,
year = {1949},
author = {BERGER, FM},
title = {The pharmacological properties of 2-methyl,2-n-amyl-4-hydroxymethyl-1,3-dioxolane (glyketal) a new blocking agent of interneurons.},
journal = {The Journal of pharmacology and experimental therapeutics},
volume = {96},
number = {3},
pages = {213-223},
pmid = {18133072},
issn = {0022-3565},
mesh = {*Dioxolanes ; *Interneurons ; },
}

*Dioxolanes
*Interneurons

@article {pmid18131870,
year = {1949},
author = {SOLLMANN, T},
title = {Correlation of the aquarium goldfish toxicities of some phenols, quinones, and other benzene derivatives with their inhibition of autooxidative reactions.},
journal = {The Journal of general physiology},
volume = {32},
number = {6},
pages = {671-679},
doi = {10.1085/jgp.32.6.671},
pmid = {18131870},
issn = {0022-1295},
mesh = {Animals ; Benzene/*toxicity ; *Benzene Derivatives ; *Fishes ; *Goldfish ; *Hydroquinones ; *Phenols ; *Quinones ; },
abstract = {Hydroquinone when added to the aquarium water was found to be about a hundred times more toxic than phenol, to goldfish (and to Daphnia magna), but is only about twice as toxic when injected into fish or mammals. Tertiarybutyl catechol shows a similar high toxicity in the aquarium, while the toxicity of catechol, resorcinol, and pyrogallol approaches more closely that of phenol. As the substances of high aquarium toxicity are known to inhibit many oxidative and polymerizing autocatalytic "chain reactions," rank correlations were tabulated between the recorded inhibitory potency of various substances in these processes, and their aquarium toxicity for goldfish. The correlation between aquarium fish toxicity and electric oxidation potential (P 0.09) is more than suggestive, and becomes still more so if explainable discrepancies are excluded. Antioxidant fat stabilizers show suggestive correlation with fish toxicity (0.20), and better with electric oxidation potential (0.10). The photographic reduction potential gives suggestive correlation with fish toxicity (0.20) and somewhat better with the oxidation potential (0.15). The gasoline induction period correlation is more than suggestive with the oxidation potential (0.099), but rather poor for fish toxicity (0.265). The rubber anti-aging potency gives only poor correlation (0.39) with fish toxicity. The reasons for these divergencies are not clear; they may perhaps be connected with the solvent properties of the substrate. As an example, Lea (p. 175) cites that 0.01 per cent of maleic acid prevents rancidity of fats, but is rendered ineffective by the presence of water. Taken by themselves, no one of the P values is entirely convincing of the relationships stressed in this paper. However, the consistent finding of relatively small values of P lends considerable weight to the hypothesis that these chemicals act in a related manner; and that the chemical activity of a substance may furnish useful suggestions of its biologic potency, perhaps more so than the chemical constitution as such. The aquarium toxicity, for goldfish is a convenient means of classifying the biologic potency.},
}

Animals
Benzene/*toxicity
*Benzene Derivatives
*Fishes
*Goldfish
*Hydroquinones
*Phenols
*Quinones

@article {pmid18145472,
year = {1949},
author = {JAROWSKI, CI and McPHAIL, MK},
title = {The antipyretic action of some derivatives of salicylic acid, p-aminophenol, and dihydropyrazolon.},
journal = {Journal of the American Pharmaceutical Association. American Pharmaceutical Association},
volume = {38},
number = {6},
pages = {349-352},
doi = {10.1002/jps.3030380618},
pmid = {18145472},
mesh = {*Aminophenols ; *Analgesics, Non-Narcotic ; *Antipyretics ; *Salicylic Acid ; },
}

*Aminophenols
*Analgesics, Non-Narcotic
*Antipyretics
*Salicylic Acid

@article {pmid18127502,
year = {1949},
author = {BERNSTEIN, ET and SACHS, PM},
title = {Pigmentary disturbance following exposure to monobenzyl ether of hydroquinone.},
journal = {Archives of dermatology and syphilology},
volume = {59},
number = {5},
pages = {542-548},
doi = {10.1001/archderm.1949.01520300052008},
pmid = {18127502},
issn = {0096-6029},
mesh = {*Biological Products ; *Ether ; *Ethers ; Humans ; Hydroquinones/*toxicity ; *Pigmentation ; *Skin Pigmentation ; },
}

*Biological Products
*Ether
*Ethers
Humans
Hydroquinones/*toxicity
*Pigmentation
*Skin Pigmentation

@article {pmid18224952,
year = {1949},
author = {ABDEL FATTAH ALY ISMAIL, },
title = {A quinonoid structure for hydroquinone pyridinium salts of organic acids.},
journal = {Nature},
volume = {163},
number = {4145},
pages = {565},
doi = {10.1038/163565b0},
pmid = {18224952},
issn = {0028-0836},
mesh = {*Hydroquinones ; *Organic Chemicals ; *Pyridines ; *Quinones ; *Salts ; },
}

*Hydroquinones
*Organic Chemicals
*Pyridines
*Quinones
*Salts

@article {pmid18208258,
year = {1949},
author = {CARVER, JH and WHITE, GK},
title = {Methylene bromide as a quenching agent in Geiger-Müller counters.},
journal = {Nature},
volume = {163},
number = {4144},
pages = {526},
doi = {10.1038/163526b0},
pmid = {18208258},
issn = {0028-0836},
mesh = {*Bromides ; *Hydrocarbons, Brominated ; *Radiometry ; },
}

*Bromides
*Hydrocarbons, Brominated
*Radiometry

@article {pmid18120016,
year = {1949},
author = {HODGE, HC and STERNER, JH},
title = {Short-term toxicity tests on the mono and di methyl ethers of hydroquinone.},
journal = {The Journal of industrial hygiene and toxicology},
volume = {31},
number = {2},
pages = {79-92},
pmid = {18120016},
issn = {0095-9030},
mesh = {Humans ; Hydroquinones/*toxicity ; *Methyl Ethers ; *Toxicity Tests ; },
}

Humans
Hydroquinones/*toxicity
*Methyl Ethers
*Toxicity Tests

@article {pmid18116445,
year = {1949},
author = {LEIN, J and LEIN, PS},
title = {Stabilization of the thromboplastic lipid by hydroquinone.},
journal = {Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)},
volume = {70},
number = {3},
pages = {446-448},
doi = {10.3181/00379727-70-16955},
pmid = {18116445},
issn = {0037-9727},
mesh = {*Blood ; Humans ; *Hydroquinones ; *Lipids ; },
}

*Blood
Humans
*Hydroquinones
*Lipids

@article {pmid18113533,
year = {1949},
author = {WINTERSTEINER, O and KLINGSBERG, A},
title = {The partial methylation of methyl beta-D-xylopyranoside with methyl sulfate.},
journal = {Journal of the American Chemical Society},
volume = {71},
number = {3},
pages = {939-942},
doi = {10.1021/ja01171a048},
pmid = {18113533},
issn = {0002-7863},
mesh = {Humans ; Methylation ; *Methylglycosides ; *Sulfuric Acid Esters ; },
}

Humans
Methylation
*Methylglycosides
*Sulfuric Acid Esters

@article {pmid18130433,
year = {1949},
author = {GARTON, GA and WILLIAMS, RT},
title = {Studies in detoxication; the fates of quinol and resorcinol in the rabbit in relation to the metabolism of benzene.},
journal = {The Biochemical journal},
volume = {44},
number = {2},
pages = {234-238},
pmid = {18130433},
issn = {0264-6021},
mesh = {Animals ; *Benzene ; *Hydroquinones ; Rabbits ; *Resorcinols ; },
}

Animals
*Benzene
*Hydroquinones
Rabbits
*Resorcinols

@article {pmid18129546,
year = {1949},
author = {CORTI, UA},
title = {Results of the methylation of tyrosine with dimethyl sulfate and some derivatives of N-methyltyramine.},
journal = {Helvetica chimica acta},
volume = {32},
number = {3},
pages = {681-686},
doi = {10.1002/hlca.19490320309},
pmid = {18129546},
issn = {0018-019X},
mesh = {*Coloring Agents ; Humans ; *Sulfuric Acid Esters ; },
}

*Coloring Agents
Humans
*Sulfuric Acid Esters

@article {pmid18127452,
year = {1949},
author = {PORTEOUS, JW and WILLIAMS, RT},
title = {Studies in detoxication; the metabolism of benzene; the isolation of phenol, catechol, quinol and hydroxyquinol from ethereal sulphate fraction of the urine of rabbits receiving benzene orally.},
journal = {The Biochemical journal},
volume = {44},
number = {1},
pages = {56-61},
pmid = {18127452},
issn = {0264-6021},
mesh = {Animals ; Benzene/*toxicity ; *Catechols ; *Hydroquinones ; *Phenol ; *Phenols ; Rabbits ; *Sulfates ; Urine/*chemistry ; },
}

Animals
Benzene/*toxicity
*Catechols
*Hydroquinones
*Phenol
*Phenols
Rabbits
*Sulfates
Urine/*chemistry

@article {pmid18127451,
year = {1949},
author = {PORTEOUS, JW and WILLIAMS, RT},
title = {Studies in detoxication; the metabolism of benzene; the determination of phenol in urine with 2:6-dichloroquinonechloroimide; the excretion of phenol, glucuronic acid and ethereal sulphate by rabbits receiving benzene and phenol; observations on the determination of catechol, quinol and muconic acid in urine.},
journal = {The Biochemical journal},
volume = {44},
number = {1},
pages = {46-55},
pmid = {18127451},
issn = {0264-6021},
mesh = {Animals ; Benzene/*toxicity ; *Catechols ; *Glucuronic Acid ; Humans ; *Hydroquinones ; *Phenol ; *Phenols ; Rabbits ; *Sorbic Acid ; *Sulfates ; Urine/*chemistry ; },
}

Animals
Benzene/*toxicity
*Catechols
*Glucuronic Acid
Humans
*Hydroquinones
*Phenol
*Phenols
Rabbits
*Sorbic Acid
*Sulfates
Urine/*chemistry

@article {pmid15394446,
year = {1949},
author = {TARNOKY, AL and BREWS, VA},
title = {Determination of p-aminosalicylic acid as m-aminophenol.},
journal = {The Biochemical journal},
volume = {45},
number = {4},
pages = {508-511},
pmid = {15394446},
issn = {0264-6021},
mesh = {*Aminophenols ; *Aminosalicylic Acid ; *Phenols ; },
}

*Aminophenols
*Aminosalicylic Acid
*Phenols

@article {pmid18105655,
year = {1948},
author = {RICHARDS, RK and KUETER, KE},
title = {Antagonism of rutin to capillary effects of sodium bisulfite and procaine.},
journal = {The Journal of pharmacology and experimental therapeutics},
volume = {94},
number = {4},
pages = {372-381},
pmid = {18105655},
issn = {0022-3565},
mesh = {*Capillaries ; Humans ; *Procaine ; Rutin/*pharmacology ; *Sulfites ; },
}

*Capillaries
Humans
*Procaine
Rutin/*pharmacology
*Sulfites

@article {pmid17830648,
year = {1948},
author = {Berger, FM and Boekelheide, V and Tarbell, DS},
title = {The Pharmacological Properties of Some 2-Substituted-4-hydroxymethyl-1,3-dioxolanes.},
journal = {Science (New York, N.Y.)},
volume = {108},
number = {2812},
pages = {561-562},
doi = {10.1126/science.108.2812.561},
pmid = {17830648},
issn = {0036-8075},
mesh = {*Dioxolanes ; },
}

*Dioxolanes

@article {pmid18102977,
year = {1948},
author = {SCHULZE, WA and CROUCH, WW},
title = {Composition of butadiene-styrene copolymers from sodium-catalyzed polymerization.},
journal = {Journal of the American Chemical Society},
volume = {70},
number = {11},
pages = {3891-3893},
doi = {10.1021/ja01191a107},
pmid = {18102977},
issn = {0002-7863},
mesh = {*Butadienes ; *Ions ; *Polymerization ; *Polystyrenes ; *Sodium ; },
}

*Butadienes
*Ions
*Polymerization
*Polystyrenes
*Sodium

@article {pmid18102963,
year = {1948},
author = {MARVEL, CS and WILLIAMS, JL},
title = {2-Alkyl-1,3-butadienes.},
journal = {Journal of the American Chemical Society},
volume = {70},
number = {11},
pages = {3842-3846},
doi = {10.1021/ja01191a089},
pmid = {18102963},
issn = {0002-7863},
mesh = {*Butadienes ; },
}

*Butadienes

@article {pmid18102947,
year = {1948},
author = {McELVAIN, SM and CURRY, MJ},
title = {Ketene acetals; 2-methylene-1,3-dioxolanes and 1,3-dioxanes.},
journal = {Journal of the American Chemical Society},
volume = {70},
number = {11},
pages = {3781-3786},
doi = {10.1021/ja01191a071},
pmid = {18102947},
issn = {0002-7863},
mesh = {*Acetals ; *Dioxanes ; *Dioxolanes ; *Ethylenes ; *Ketones ; },
}

*Acetals
*Dioxanes
*Dioxolanes
*Ethylenes
*Ketones

@article {pmid18891886,
year = {1948},
author = {CROWELL, TI and HAMMETT, LP},
title = {Kinetics of the reactions of thiosulfate ion with ethyl, propyl and isopropyl bromides.},
journal = {Journal of the American Chemical Society},
volume = {70},
number = {10},
pages = {3444-3450},
doi = {10.1021/ja01190a067},
pmid = {18891886},
issn = {0002-7863},
mesh = {*Hydrocarbons, Brominated ; Kinetics ; *Thiosulfates ; },
}

*Hydrocarbons, Brominated
Kinetics
*Thiosulfates

@article {pmid18101444,
year = {1948},
author = {LORA-TAMAYO, M and LEON, JL},
title = {The condensation of 2 :3-dimethyl-l :3-butadiene and p-benzo-quinone.},
journal = {Journal of the Chemical Society},
volume = {3},
number = {},
pages = {1499-1501},
pmid = {18101444},
issn = {0368-1769},
mesh = {*Benzoquinones ; *Butadienes ; Humans ; },
}

*Benzoquinones
*Butadienes
Humans

@article {pmid18885618,
year = {1948},
author = {FLINN, FB and BRODIE, BB},
title = {The effect on the pain threshold of N-acetyl p-aminophenol, a product derived in the body from acetanilide.},
journal = {The Journal of pharmacology and experimental therapeutics},
volume = {94},
number = {1},
pages = {76},
pmid = {18885618},
issn = {0022-3565},
mesh = {*Acetaminophen ; *Acetanilides ; *Aminophenols ; Humans ; *Pain Threshold ; },
}

*Acetaminophen
*Acetanilides
*Aminophenols
Humans
*Pain Threshold

@article {pmid18885610,
year = {1948},
author = {BRODIE, BB and AXELROD, J},
title = {The estimation of acetanilide and its metabolic products, aniline, N-acetyl p-aminophenol and p-amino-phenol, free and total conjugated, in biological fluids and tissues.},
journal = {The Journal of pharmacology and experimental therapeutics},
volume = {94},
number = {1},
pages = {22-28},
pmid = {18885610},
issn = {0022-3565},
mesh = {*Acetaminophen ; *Acetanilides ; *Aminophenols ; *Aniline Compounds ; Humans ; *Phenol ; *Phenols ; },
}

*Acetaminophen
*Acetanilides
*Aminophenols
*Aniline Compounds
Humans
*Phenol
*Phenols

@article {pmid18104376,
year = {1948},
author = {KIRBY, AH},
title = {The action of 2-aminofluorene in three pure strains of mice.},
journal = {British journal of cancer},
volume = {2},
number = {3},
pages = {294-300},
doi = {10.1038/bjc.1948.35},
pmid = {18104376},
issn = {0007-0920},
mesh = {Animals ; *Fluorenes ; Mice ; },
}

Animals
*Fluorenes
Mice

@article {pmid18884178,
year = {1948},
author = {KARCZMAR, AG},
title = {Influence of methyl bis amine, hydroquinone and thyroxin on regeneration in urodele larvae.},
journal = {The Anatomical record},
volume = {101},
number = {4},
pages = {712},
pmid = {18884178},
issn = {0003-276X},
mesh = {*Amines ; Animals ; Hydroquinones/*pharmacology ; *Larva ; *Regeneration ; *Thyroxine ; *Urodela ; },
}

*Amines
Animals
Hydroquinones/*pharmacology
*Larva
*Regeneration
*Thyroxine
*Urodela

@article {pmid18869429,
year = {1948},
author = {PALIN, DE and POWELL, HM},
title = {The structure of molecular compounds; the clathrate compound of quinol and methanol.},
journal = {Journal of the Chemical Society},
volume = {2},
number = {},
pages = {571-574},
doi = {10.1039/jr9480000571},
pmid = {18869429},
issn = {0368-1769},
mesh = {*Hydroquinones ; *Methanol ; },
}

*Hydroquinones
*Methanol

@article {pmid18913390,
year = {1948},
author = {PARMENTIER, R and DUSTIN, P},
title = {Early effects of hydroquinone on mitosis.},
journal = {Nature},
volume = {161},
number = {4092},
pages = {527},
doi = {10.1038/161527a0},
pmid = {18913390},
issn = {0028-0836},
mesh = {*Cell Division ; Humans ; *Hydroquinones ; *Mitosis ; },
}

*Cell Division
Humans
*Hydroquinones
*Mitosis

@article {pmid18880640,
year = {1948},
author = {LACASSAGNE, A and BUU-HOI, NP},
title = {Contribution to the study of the carcinogenic power of 2-aminofluorene.},
journal = {Comptes rendus des seances de la Societe de biologie et de ses filiales},
volume = {142},
number = {7-8},
pages = {481-483},
pmid = {18880640},
issn = {0037-9026},
mesh = {*Fluorenes ; Humans ; Neoplasms/*etiology ; },
}

*Fluorenes
Humans
Neoplasms/*etiology

@article {pmid18911175,
year = {1948},
author = {MILLER, JA and MILLER, EC},
title = {The carcinogenicity of certain derivatives of p-dimethylaminozobenz in the rat.},
journal = {The Journal of experimental medicine},
volume = {87},
number = {2},
pages = {139-156},
pmid = {18911175},
issn = {0022-1007},
mesh = {*Aminophenols ; Animals ; *Azo Compounds ; *Carcinogens ; *Nitro Compounds ; *Phenylenediamines ; Rats ; *p-Aminoazobenzene ; *p-Dimethylaminoazobenzene ; },
abstract = {1. Eighteen known or possible metabolites of the hepatic carcinogen 4- (or p-) dimethylaminoazobenzene were tested for carcinogenic activity in the rat. Of these compounds only 4-monomethylaminoazobenzene, a known metabolite, proved to be active. Eight compounds, which appear to be metabolites of the dye, were inactive; these included 4-aminoazobenzene, 4'-hydroxy-4-monomethylaminoazobenzene, 4'-hydroxy-4-aminoazobenzene, N-methyl-p-phenylenediamine, p-phenylenediamine, aniline, p-aminophenol, and o-aminophenol. Nine compounds which may possibly be metabolites also were inactive; these compounds were 4'-hydroxy-, 3'-hydroxy-, and 2'-hydroxy-4-dimethylaminoazobenzene, 4-formylaminoazobenzene, 4-hydroxyazobenzene, 2, 4'-diamino-5-dimethylaminodiphenyl, 3-dimethylaminocarbazole, N,N-dimethyl-p-phenylenediamine, and p-hydroquinone. A mixture of 9 known and possible metabolites was also found to be inactive. These data indicate that the primary carcinogen operative in tumor formation by 4-dimethylaminoazobenzene is probably an azo dye closely related to the parent carcinogen. This conclusion is supported by recent work from this laboratory which indicates that the primary carcinogen consists of either or both of the protein-bound dyes found in the liver, i.e. 4-monomethylaminoazobenzene and an unidentified polar aminoazo dye, and that the formation of bound dye constitutes one of the first steps in this carcinogenic process. 2. The carcinogenic activities of 19 other compounds related to 4-dimethyl-aminoazobenzene were tested to obtain more information on the structural features needed for a 4-aminoazo dye to possess strong activity in the rat. 3'-Methyl-4-monomethylaminoazobenzene and the corresponding dimethylamino derivative were nearly twice as active and 4-ethylmethylaminoazobenzene had the same activity as 4-dimethylaminoazobenzene. As tested 3'-nitro- and 3'-chloro-4-dimethylaminoazobenzene both had about the same activity as 4-dimethylaminoazobenzene; however, since the 3'-nitro derivative was incompletely absorbed its real activity appears to be about 1(1/2) times that of 4-dimethylaminoazobenzene. 2'-Nitro- and 2'-chloro-4-dimethylaminoazobenzene were about one-half to one-third as active and 4'-chloro-4-dimethylaminoazobenzene was approximately one-fourth as active as the parent dye. 3'-Ethoxy-4-dimethylaminoazobenzene and 3-methyl-4-monomethylaminoazobenzene exhibited only slight carcinogenic activity. The following compounds proved inactive: the benzamide of N,N-dimethyl-p-phenylenediamine; the diethyl, monoethyl, benzylmethyl, beta-hydroxyethylmethyl, and formyl derivatives of 4-aminoazobenzene on the amino group; and the 3-methyl, 3', 5'-dimethyl, 2',5'-dimethyl, and 2',4'-dimethyl derivatives of 4-dimethylaminoazobenzene. From the available data two conditions appear to be essential if a dye is to possess high activity: (1) at least one methyl group must be attached to the amino group together with the proper second substituent, and (2) the rings must bear either no substituents or carry only certain substituents, preferably in the 3' position. 3. The data on the carcinogenicity of the 2'-, 3'-, or 4'-methyl, chloro, and nitro derivatives of 4-dimethylaminoazobenzene show that the position of these groups determines the carcinogenicity of these compounds to a greater extent than does the type of group. The activity relationship was 3' > 2' > 4'. 4. Primary, secondary, and tertiary aminoazo dyes were determined in the livers and blood of rats fed aminoazo dyes which differed in the substituents on the amino group. The data show that deethylation of 4-diethyl-, 4-monoethyl-, and 4-ethylmethylaminoazobenzene occurs in vivo just as 4-dimethyl- and 4-monomethylaminoazobenzene are demethylated in vivo. However, 4-benzylmethylaminoazobenzene and 4-beta-hydroxyethylmethylaminoazobenzene were dealkylated only slightly under similar conditions. 5. The following new compounds are described: 4-ethylmethyl-, 4-monoethyl-, 4-benzylmethyl-, and 4-beta-hydroxyethylmethylaminoazobenzene; 4'-hydroxy-, 3-methyl-, and 3'-methyl-4-monomethylaminoazobenzene; 2'-hydroxy-, 3'-hydroxy, 3-methyl-, 3'-ethoxy-, 3', 5'-dimethyl-, 2', 5'-dimethyl-, and 2',4'-dimethyl-4-dimethylaminoazobenzene.},
}

*Aminophenols
Animals
*Azo Compounds
*Carcinogens
*Nitro Compounds
*Phenylenediamines
Rats
*p-Aminoazobenzene
*p-Dimethylaminoazobenzene

@article {pmid18899661,
year = {1948},
author = {POWELL, HM and RIESZ, P},
title = {Beta-quinol; an example of the firm union of molecules without the formation of chemical bonds between them.},
journal = {Nature},
volume = {161},
number = {4080},
pages = {52},
doi = {10.1038/161052c0},
pmid = {18899661},
issn = {0028-0836},
mesh = {*Hydroquinones ; *Quinones ; },
}

*Hydroquinones
*Quinones

@article {pmid18122557,
year = {1948},
author = {AHUJA, },
title = {Occupational eye damage to workers in hydroquinone factories.},
journal = {Klinische Monatsblatter fur Augenheilkunde und fur augenarztliche Fortbildung},
volume = {113},
number = {2},
pages = {177},
pmid = {18122557},
issn = {0344-6360},
mesh = {Humans ; Hydroquinones/*toxicity ; },
}

Humans
Hydroquinones/*toxicity

@article {pmid18919413,
year = {1947},
author = {COGAN, DG and GRANT, WM},
title = {Corneal and conjunctival pigmentation among workers in hydroquinone.},
journal = {Archives of ophthalmology (Chicago, Ill. : 1929)},
volume = {38},
number = {6},
pages = {847},
doi = {10.1001/archopht.1947.00900010870012},
pmid = {18919413},
mesh = {*Conjunctiva ; *Conjunctival Diseases ; *Cornea ; *Corneal Diseases ; Humans ; Hydroquinones/*toxicity ; *Pigmentation ; *Pigmentation Disorders ; },
}

*Conjunctiva
*Conjunctival Diseases
*Cornea
*Corneal Diseases
Humans
Hydroquinones/*toxicity
*Pigmentation
*Pigmentation Disorders

@article {pmid18919409,
year = {1947},
author = {ANDERSON, B},
title = {Corneal and conjunctival pigmentation among workers engaged in manufacture of hydroquinone.},
journal = {Archives of ophthalmology (Chicago, Ill. : 1929)},
volume = {38},
number = {6},
pages = {812-826},
doi = {10.1001/archopht.1947.00900010831007},
pmid = {18919409},
mesh = {*Conjunctiva ; *Conjunctival Diseases ; *Cornea ; *Corneal Diseases ; Humans ; *Hydroquinones ; *Pigmentation ; *Pigmentation Disorders ; },
}

*Conjunctiva
*Conjunctival Diseases
*Cornea
*Corneal Diseases
Humans
*Hydroquinones
*Pigmentation
*Pigmentation Disorders

@article {pmid20256355,
year = {1947},
author = {RAAB, C and GROSZ, S},
title = {Conjunctivitis in exposure to dimethyl-sulphate.},
journal = {The British journal of ophthalmology},
volume = {31},
number = {8},
pages = {509},
pmid = {20256355},
issn = {0007-1161},
mesh = {*Conjunctivitis ; Humans ; *Sulfates ; Sulfur/*pharmacology ; *Sulfuric Acid Esters ; },
}

*Conjunctivitis
Humans
*Sulfates
Sulfur/*pharmacology
*Sulfuric Acid Esters

@article {pmid20250932,
year = {1947},
author = {MORELLI, E and MISLER, G},
title = {Action of 2-aminofluorene on moulds.},
journal = {Nature},
volume = {160},
number = {4053},
pages = {21},
doi = {10.1038/160021b0},
pmid = {20250932},
issn = {0028-0836},
mesh = {*Fluorenes ; *Fungi ; Humans ; },
}

*Fluorenes
*Fungi
Humans

@article {pmid20249075,
year = {1947},
author = {GREENBERG, LA and LESTER, D},
title = {The metabolic fate of acetanilid and other aniline derivatives; the role of p-aminophenol in the production of methemoglobinemia after acetanilid.},
journal = {The Journal of pharmacology and experimental therapeutics},
volume = {90},
number = {2},
pages = {150-153},
pmid = {20249075},
issn = {0022-3565},
mesh = {*Acetanilides ; *Aminophenols ; Aniline Compounds/metabolism ; *Methemoglobinemia ; },
}

*Acetanilides
*Aminophenols
Aniline Compounds/metabolism
*Methemoglobinemia

@article {pmid18170357,
year = {1947},
author = {Stern, HJ},
title = {CONJUNCTIVITIS DUE TO EXPOSURE TO DIMETHYL-SULFATE.},
journal = {The British journal of ophthalmology},
volume = {31},
number = {6},
pages = {373-375},
doi = {10.1136/bjo.31.6.373},
pmid = {18170357},
issn = {0007-1161},
mesh = {Conjunctivitis/*etiology ; Humans ; *Industry ; *Occupational Diseases ; *Occupations ; *Sulfates ; Sulfuric Acid Esters/*toxicity ; },
}

Conjunctivitis/*etiology
Humans
*Industry
*Occupational Diseases
*Occupations
*Sulfates
Sulfuric Acid Esters/*toxicity

@article {pmid20263735,
year = {1947},
author = {CASTRO BARRETTO, },
title = {[Functional and therapeutic synergy of complex B].},
journal = {Resenha clinico-cientifica},
volume = {16},
number = {5},
pages = {190-192},
pmid = {20263735},
issn = {0048-735X},
mesh = {Humans ; *Hydroquinones ; *Vitamin B Complex ; *Vitamins ; },
}

Humans
*Hydroquinones
*Vitamin B Complex
*Vitamins

@article {pmid20251370,
year = {1947},
author = {JANZ, GJ},
title = {Concerning the theoretical aspects of the reaction of cyanogen and 1,3-butadiene.},
journal = {Canadian journal of research},
volume = {25},
number = {3},
pages = {331},
doi = {10.1139/cjr47b-036},
pmid = {20251370},
mesh = {*Butadienes ; Humans ; *Nitriles ; },
}

*Butadienes
Humans
*Nitriles

@article {pmid20251364,
year = {1947},
author = {JANZ, GJ and ASCAH, RG and KEENAN, AG},
title = {The reaction of cyanogen with 1,3-butadiene.},
journal = {Canadian journal of research},
volume = {25},
number = {3},
pages = {272-282},
doi = {10.1139/cjr47b-030},
pmid = {20251364},
mesh = {*Butadienes ; Humans ; *Nitriles ; },
}

*Butadienes
Humans
*Nitriles

@article {pmid20294301,
year = {1947},
author = {DREIZEN, S and MANN, AW},
title = {The influence of sodium bisulphite on acid production in saliva.},
journal = {Journal of dental research},
volume = {26},
number = {2},
pages = {93-97},
doi = {10.1177/00220345470260021101},
pmid = {20294301},
issn = {0022-0345},
mesh = {*N-Acetylneuraminic Acid ; *Saliva ; *Sodium ; *Sulfites ; },
}

*N-Acetylneuraminic Acid
*Saliva
*Sodium
*Sulfites

@article {pmid20256072,
year = {1947},
author = {DHERE, C and LASZT, L},
title = {Fluorescence reactions of some steroids (adrenal and sex hormones) with neutral methyl sulfate.},
journal = {Comptes rendus hebdomadaires des seances de l'Academie des sciences},
volume = {224},
number = {9},
pages = {681-683},
pmid = {20256072},
issn = {0001-4036},
mesh = {Humans ; *Steroids ; *Sulfuric Acid Esters ; },
}

Humans
*Steroids
*Sulfuric Acid Esters

@article {pmid20280653,
year = {1947},
author = {HARRIS, PN},
title = {Production of tumors in rats by 2-aminofluorene and 2-acetylaminofluorene; failure of liver extract and of dietary protein level to influence liver tumor production.},
journal = {Cancer research},
volume = {7},
number = {2},
pages = {88-94},
pmid = {20280653},
issn = {0008-5472},
mesh = {*2-Acetylaminofluorene ; Animals ; *Diet ; *Dietary Proteins ; *Fluorenes ; *Liver ; *Liver Extracts ; *Liver Neoplasms ; *Neoplasms ; *Neoplasms, Experimental ; *Proteins ; Rats ; },
}

*2-Acetylaminofluorene
Animals
*Diet
*Dietary Proteins
*Fluorenes
*Liver
*Liver Extracts
*Liver Neoplasms
*Neoplasms
*Neoplasms, Experimental
*Proteins
Rats

@article {pmid20285024,
year = {1947},
author = {MARION, L and FARMILO, CG},
title = {Note on the preparation of 1-methoxy-1,3-butadiene.},
journal = {Canadian journal of research},
volume = {25},
number = {1},
pages = {118-120},
doi = {10.1139/cjr47b-014},
pmid = {20285024},
mesh = {*Butadienes ; Humans ; },
}

*Butadienes
Humans

@article {pmid18898893,
year = {1947},
author = {BOYMOND, P and JADASSOHN, W},
title = {About chrysarobin.},
journal = {Dermatologica},
volume = {94},
number = {4},
pages = {228-230},
pmid = {18898893},
issn = {0011-9075},
mesh = {*Anthraquinones ; Humans ; },
}

*Anthraquinones
Humans

@article {pmid20282417,
year = {1946},
author = {KAUFMANN, S and ROSENKRANZ, G and LOPEZ, J},
title = {Halogenated derivatives of methyleugenol; 6-bromomethyleugenol glycol and 6-bromohomover atraldehyde.},
journal = {Journal of the American Chemical Society},
volume = {68},
number = {12},
pages = {2733},
doi = {10.1021/ja01216a513},
pmid = {20282417},
issn = {0002-7863},
mesh = {*Benzaldehydes ; *Eugenol ; *Glycols ; *Halogenation ; },
}

*Benzaldehydes
*Eugenol
*Glycols
*Halogenation

@article {pmid20282496,
year = {1946},
author = {STAHMANN, MA and GOLUMBIC, C},
title = {Chemical reactions of mustard gas and related compounds; the chemistry of bis(beta-chloroethyl)-sulfone, divinyl sulfone and divinyl sulfoxide.},
journal = {The Journal of organic chemistry},
volume = {11},
number = {6},
pages = {719-735},
doi = {10.1021/jo01176a013},
pmid = {20282496},
issn = {0022-3263},
mesh = {*Butadienes ; Mustard Gas/*chemistry ; *Sulfides ; *Sulfones ; *Sulfoxides ; },
}

*Butadienes
Mustard Gas/*chemistry
*Sulfides
*Sulfones
*Sulfoxides

@article {pmid20982750,
year = {1946},
author = {DEY, BB and GOVINDACHARI, TR and RAJAGOPALAN, SC},
title = {Electrolytic reduction of nitro compounds; the electrolytic reduction of nitrobenzene to para aminophenol.},
journal = {Journal. Council for Scientific and Industrial Research (Australia)},
volume = {4},
number = {},
pages = {574-581},
pmid = {20982750},
issn = {0368-1734},
mesh = {*Aminophenols ; *Electrolysis ; *Electrolytes ; *Nitro Compounds ; *Nitrobenzenes ; },
}

*Aminophenols
*Electrolysis
*Electrolytes
*Nitro Compounds
*Nitrobenzenes